3 Best Mushrooms for Anxiety (And Where to Buy Them)
Struggling with anxiety? You’re not alone.
According to the World Health Organization, over 264 million people worldwide suffer from anxiety-related conditions. With growing awareness around mental health, many people are now turning to natural remedies — including medicinal mushrooms — to find calm and relief.
What if we told you that mushrooms, long used in traditional healing systems, could help ease anxiety, improve mood, and support emotional balance?
In this article, you’ll learn:
How mushrooms work for anxiety
The 3 best mushrooms for anxiety relief
How to use them effectively
And where to buy high-quality mushroom supplements
How Do Mushrooms Help with Anxiety?
Medicinal mushrooms contain powerful compounds that may help relieve anxiety by interacting with your body’s neurotransmitter system, inflammation response, and gut-brain axis.
Here’s how they work:
- Neurotransmitter Support: Certain mushrooms, like Lion’s Mane and Reishi, influence key brain chemicals like serotonin and dopamine — both of which play major roles in regulating mood and anxiety.
- Anti-Inflammatory Properties: Chronic inflammation is closely linked to depression and anxiety. Medicinal mushrooms are rich in beta-glucans, terpenoids, and antioxidants that help reduce brain and body inflammation.
- Stress Hormone Regulation: Mushrooms may help regulate cortisol — your body’s primary stress hormone — which can reduce symptoms of stress and tension.
- Gut-Brain Axis Support: Inflammation can disturb your gut microbiome, affecting mood. Mushrooms may help restore gut health, indirectly supporting emotional balance.
The 3 Best Mushrooms for Anxiety Relief
1. Reishi Mushroom (Ganoderma lucidum)
Reishi is known as the “Mushroom of Immortality” — and for good reason. This adaptogen is deeply calming and promotes restful sleep, making it ideal for anxiety sufferers.
Benefits:
- Reduces cortisol and stress levels
- Supports deep relaxation
- Fights oxidative stress in the brain
- May relieve symptoms of mild depression
Research Insight:
A study involving 132 participants with neurasthenia (a stress-related condition) found that taking 1,800 mg of Reishi extract three times a day significantly reduced anxiety, fatigue, and depression.
2. Lion’s Mane Mushroom (Hericium erinaceus)
Lion’s Mane is a brain-boosting powerhouse that also supports emotional regulation. Its unique ability to stimulate nerve growth factor (NGF) makes it especially beneficial for mood, focus, and mental clarity.
Benefits:
- Promotes neuroplasticity
- Increases serotonin and dopamine levels
- Fights inflammation in the brain
- Supports better focus and memory
Research Insight:
Compounds in Lion’s Mane — hericenones and erinacines — have been shown to enhance brain function and may help combat cognitive decline, which often accompanies chronic anxiety.
3. Cordyceps (Cordyceps militaris / sinensis)
Cordyceps is best known for its energy-boosting effects, but it also offers impressive anti-anxiety benefits by lowering fatigue and reducing inflammation.
Benefits:
- Enhances physical stamina and combats burnout
- Reduces inflammatory markers
- Helps regulate stress hormones
- May improve mood and sleep
Why It Matters:
Chronic inflammation in the brain is linked to anxiety and depression. Cordyceps supports a healthy inflammation response, which can reduce stress, support cognitive performance, and promote emotional balance.
Why Inflammation Matters
Inflammation is a key contributor to anxiety and mood disorders. Chronic inflammation:
- Alters brain chemicals like cytokines, disrupting serotonin and dopamine levels
- Increases cortisol, leading to heightened stress responses
- Shrinks the hippocampus — a brain region tied to memory and emotion
- Disrupts the gut-brain connection, affecting mood through the microbiome
Using anti-inflammatory mushrooms like Cordyceps, Reishi, and Lion’s Mane may help reverse some of these effects and bring emotional relief.
How to Use Mushrooms for Anxiety
You can easily incorporate medicinal mushrooms into your wellness routine through:
Popular Forms:
- Capsules or tablets – Easy to dose, travel-friendly
- Powders – Blend into smoothies, coffee, or tea
- Tinctures – Fast absorption and flexible dosing
- Teas – A calming, traditional approach
- Edibles – Gummies or chocolates with mushroom extracts
Best Practices:
- Use daily for at least 2–4 weeks to feel noticeable effects.
- Pair with other anxiety-reducing strategies like meditation, exercise, or therapy.
- Always choose high-quality, lab-tested products.
⚠️ Consult a healthcare professional before starting any mushroom supplement, especially if you’re on medication or have underlying conditions.
Where to Buy Mushroom Supplements
Looking to get started?
You can find premium-quality medicinal mushrooms — including Reishi, Lion’s Mane, and Cordyceps — at:
All products are sourced with quality and purity in mind, making it easier for you to begin your natural anxiety relief journey with confidence.
Final Thoughts
Medicinal mushrooms are a powerful natural remedy for anxiety, backed by both tradition and emerging science. With compounds that reduce inflammation, boost neurotransmitters, and support cognitive function, mushrooms like Reishi, Lion’s Mane, and Cordyceps offer a holistic approach to emotional balance.
Whether you’re looking for deeper sleep, more focus, or calm in times of stress — these fungi may be exactly what your wellness routine needs.
❓ Frequently Asked Questions
Can mushroom supplements help with anxiety?
Yes. Mushrooms like Reishi, Cordyceps, and Lion’s Mane contain compounds that can help regulate mood, reduce stress, and support brain health. However, results may vary, and more human studies are ongoing.
What mushrooms are best for stress and anxiety?
- Reishi – for calming the nervous system
- Lion’s Mane – for mood and cognitive support
- Cordyceps – for fatigue and inflammation relief
Where can I buy mushroom supplements online?
You can shop high-quality mushroom supplements at:
👉 https://psychedelic2.com/shop-2/
