Ketamine Nasal spray
$230.00
Experience fast-acting relief from treatment-resistant depression with our prescription ketamine nasal spray. Custom-compounded by licensed pharmacies, this nasal spray offers a modern, non-invasive alternative to traditional antidepressants. Shipped discreetly and securely across the USA, Canada, UK, Australia, and Europe. Prescription required.
Description
Buy Ketamine Nasal Spray Online
Buy ketamine nasal spray online. Ketamine nasal spray is a fast-acting formulation used for treatment-resistant depression, chronic pain, PTSD, and anxiety. Available as a compounded prescription medication, this product delivers ketamine intranasally for rapid systemic absorption.
Psychedelic2 offers pharmaceutical-grade ketamine nasal spray sourced from licensed compounders.
If you’re looking to buy ketamine nasal spray online, this product description explains everything: medical use, safety, legal status, clinical research, and how to order with confidence.
What Is Ketamine Nasal Spray?
Ketamine is a dissociative anesthetic developed in the 1960s. It works primarily as an NMDA receptor antagonist, disrupting the glutamate system.
The nasal spray formulation allows for:
- Rapid absorption through the nasal mucosa
- Onset within 10 to 15 minutes
- Controlled, titrated dosing
- Non-invasive, self-administered treatment
The most well-known branded version is Spravato (esketamine), approved by the FDA for treatment-resistant depression. However, many patients use racemic ketamine nasal sprays compounded by pharmacies for off-label uses under medical supervision.
PRODUCT DETAILS
Product Name:Spravato® (Esketamine HCl)
Form: Nasal spray
Dosage: 28 mg per device
Administration: For intranasal use only
Manufactured for: Janssen Pharmaceuticals
Manufactured by: Renaissance Life
Additional Information:
Active Ingredient:Esketamine hydrochloride (the S-enantiomer of ketamine)
Indication:Typically used for treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal ideation, under medical supervision.
Usage: Requires administration in a certified healthcare setting due to potential side effects like dissociation and sedation.
Each bottle includes a medical-grade atomizing nasal spray cap.
Therapeutic Uses
Doctors prescribe ketamine nasal spray for:
- Major depressive disorder (MDD) not responding to SSRIs
- Post-traumatic stress disorder (PTSD)
- Generalized anxiety disorder (GAD)
- Bipolar depression
- Neuropathic and chronic pain (e.g., CRPS, fibromyalgia)
Stanford University, Harvard Medical School, and Johns Hopkins researchers have published positive data on ketamine’s ability to reduce suicidal ideation within hours.
Studies like this one from NIH.gov highlight ketamine’s clinical success in managing treatment-resistant mental health disorders.
How Ketamine Nasal Spray Works
Ketamine blocks NMDA receptors in the brain, disrupting overactive glutamate signaling. This helps reset dysfunctional mood and pain circuits.
Key mechanisms include:
- Increased brain-derived neurotrophic factor (BDNF)
- Synaptogenesis (growth of new neural connections)
- Enhanced prefrontal cortex activity
- Reduced amygdala hyperactivity
Unlike SSRIs, ketamine acts within hours rather than weeks.
Dose and Administration
Each spray contains 100 mg/ml of ketamine hydrochloride. This formulation is compounded and customized by certified pharmacies based on your prescription.
Dosing guide:
| Dosage Level | Volume per Dose | Frequency |
|---|---|---|
| Low (starter) | 0.1–0.2 ml | 1–2 times/week |
| Moderate | 0.3–0.4 ml | Up to 3 times/week |
| High (with doctor) | 0.5 ml or more | Under specialist care |
Always follow your prescriber’s plan. Do not exceed recommended use. Effects usually begin within 10 minutes and last 30 to 90 minutes.
What to Expect During a Ketamine Session
Ketamine nasal spray produces dissociative effects such as:
- Altered sensory perception
- Body-lightness or floaty feeling
- Visual changes with closed eyes
- Emotional release
- Temporary numbness
Many users report deep psychological insight and emotional reset following their sessions.
Ensure a quiet, safe setting and have a support person nearby for your first session. You should not drive or operate heavy machinery for 12 hours after dosing.
Side Effects and Warnings
Most people tolerate ketamine well under medical supervision.
Common side effects include:
- Mild dizziness or fatigue
- Nausea
- Mild blood pressure increase
- Dissociation or altered awareness
Serious but rare risks:
- Bladder irritation with prolonged high-dose use
- Elevated intracranial pressure
- Emergence reactions or hallucinations
Do not mix ketamine with alcohol, benzodiazepines, or opioids. Discuss with your provider if you’re on SSRIs, SNRIs, or antipsychotics.
Is Ketamine Nasal Spray Addictive?
Ketamine has a low risk of addiction when used under supervision. Abuse risk increases only when:
- Used without a prescription
- Dosed far beyond medical protocols
- Taken daily for recreational purposes
Clinicians track tolerance and signs of misuse. Most medical users do not develop dependence.
Psychedelic2 only offers ketamine nasal spray to users with a valid prescription.
How Long Does Ketamine Nasal Spray Last?
A single dose usually lasts:
- Onset: 10–15 minutes
- Peak effects: 30–45 minutes
- Total experience: 1–1.5 hours
- Afterglow: up to 24–48 hours
Antidepressant benefits can last 3 to 7 days. Maintenance doses are often weekly or biweekly.
Legal and Regulatory Status
In the United States, ketamine is classified as a Schedule III controlled substance. It is legal for medical use with a prescription.
Spravato (esketamine) is FDA-approved, while compounded ketamine sprays are prescribed off-label. Physicians and compounding pharmacies across Canada, Europe, and Australia also provide nasal ketamine under strict medical guidelines.
For more information, see DEA’s Ketamine Fact Sheet.
Why Buy Ketamine Nasal Spray Online from Psychedelic2?
Psychedelic2 connects you with legitimate, licensed pharmacies that compound ketamine under sterile, compliant conditions.
We ensure:
- Pharmacist-reviewed products
- ISO 7 cleanroom compounding
- Prescription verification
- Discreet, tracked shipping
- Ongoing customer support
You don’t need to settle for black market ketamine. You can order safer, pharmaceutical-grade ketamine online using secure channels and verified providers.
Customer Testimonials
“This nasal spray changed my life. After 15 years of depression and failed SSRIs, I finally feel stable.”
— Jennifer K., USA
“Easy to use, fast results, no side effects. I use it twice a month for PTSD with my therapist.”
— Marco T., Canada
“Way better than oral ketamine. Nasal absorption is quick and precise. I highly recommend it under doctor care.”
— Dr. H.L., UK
Where to Buy Ketamine Nasal Spray Online
You can buy ketamine nasal spray online directly through Psychedelic2’s secure order portal.
All orders require a prescription from a licensed physician. Upon upload, we forward your request to our partner compounding pharmacy. You will receive:
- A pharmacist-confirmed dosage
- Tracking number within 48 hours
- Full access to aftercare support
For other ketamine products like ketamine troches or [liquid vials], visit our ketamine product category page.
Final Advice Before You Start
- Always consult a licensed provider for psychiatric evaluation and treatment planning
- Never mix ketamine with other CNS depressants
- Set and setting matter have a calm environment for best results
- Track your response and update your prescriber regularly
- Store your nasal spray properly to preserve potency
If you’re seeking relief from chronic depression, anxiety, or pain, and other treatments have failed, ketamine nasal spray may offer an alternative.
Psychedelic2 helps you access this option safely, legally, and with full transparency.





Jennifer –
This nasal spray changed my life . After 15 years of depression and failed SSRIs , I finally feel stable and the delivery service of psychedelic2 dispensary so reliable package arrived on time